G&P Biosciences provides custom assay development services tailored to your R&D needs. We deliver specialized, reliable solutions to two major categories of bioassays, immunoassays and cell-based assays. We can develop and optimize enzyme-linked immunosorbent assays (ELISA), ligand-receptor binding and neutralization assays as well as various cellular assays, such as cell proliferation, antibody effector function (ADCC & CDC) and reporter assays. We also offer custom protein array for screening protein-protein interaction or profiling the specificity of your antibody or biologic of interest. Our dedicated project team will work closely with you through every step of the process to deliver the high-quality bioassay you expect.

Custom Immunoassay Development

(Service Code: DS-001)

We provide custom immunoassay development for quantitative measurement of your protein of interest. Leveraging our protein and hybridoma antibody generation capability, we can start by producing recombinant target antigen for direct ELISA with immobilized antigen. The assay is useful for characterizing antigen-antibody binding or quantifying antigen-reactive antibody titers in complex samples (e.g., pharmacokinetic assay for a therapeutic antibody). We can also deliver antibody pair(s) (e.g., capture antibody & biotinylated detection antibody) that offer high signal to noise detection of multiple epitopes of the target antigen, thus amenable to so-called “sandwich” ELISA.  Our services are project-based and custom-made according to your requirements. Upon receipt of your request, our project team will discuss with you the experimental design, plan, cost estimates, and delivery specifications.

Custom Cell-based Assay Development

(Service Code: DS-002)

Cell-based assays are widely used in basic research, drug discovery, and process development to determine the biological activity of a substance or product by measuring its physiological response.  Cell-based assays are important in studying the function of a gene or protein and establishing efficacy & safety profile for a biopharmaceutical product. G&P Biosciences has experience and expertise in developing, validating and conducting custom cellular assays in many applications:

• Cell-based binding, stimulation or neutralization assays, e.g., cell-ELISA, cytokine production, protein phosphorylation & degradation
• Cell-based potency or efficacy assays, e.g., cell survival, apoptosis, proliferation, migration, differentiation & angiogenesis
• Cell-based reporter assays, e.g., signal pathway activation or inhibition using absorbance, fluorescence or luminescence readout
• Cell-based antibody function assays, e.g., antibody dependent cell cytotoxicity (ADCC), complement dependent cytotoxicity (CDC) & antibody internalization

Our services are project-based and custom-made according to your requirements. Upon receipt of your request, our project team will discuss with you the experimental design, plan, cost estimates, and delivery specifications. 

Custom Protein Array & Profiling

(Service Code: DS-003)

We provide custom protein array services for screening protein-protein interaction or profiling the specificity of your antibody or biological sample. Leveraging our high-through cloning & expression technologies in combination with our pre-made gene clones and recombinant proteins, we can rapidly profile your biological sample for its reactivity against any custom array of human or murine gene products. Our services include custom array preparation, sample analysis, comprehensive data analysis and reporting. We can prepare the custom protein array based on your specifications using purified recombinant proteins, crude cell extracts, or cell lines that express individual proteins to be screened against.  We can deliver the custom array to you or conduct the screening service for you.  We will work closely with you to design and develop the solutions most suitable for you. Upon receipt of your request, our team will discuss with you the experimental plan, cost estimates, timelines and delivery specifications. 

Bundled Service Package

One-Stop Shop Solution: Gene-To-Assay

(Service Code:DS-G2A)

We offer bundled custom immunoassay development services, “Gene-to-Assay”, a one-stop shop solution with standardized workflow and turnaround time. Bundle discount is included when you order antigen preparation, antibody generation and screening as well as assay development and validation from G&P Biosciences at the same time. Our one-stop shop services will significantly reduce the time and cost for your assay development.In general our bundled services include following three major steps: (1)gene cloning & antigen preparation (2) immunization & antibody screening; (3) assay development & optimization. We will validate the assay by constructing a standard curve using the recombinant antigen we prepare. Upon request, we can also validate the assay with transfected cells (or lysates) or biological samples containing the native antigen. 

To request this bundled service, simply provide us the DNA nucleotide or protein amino acid sequence for the target antigen of interest, and indicate the format and parameter of custom assay to be delivered. Upon receipt of your request, our service team will contact you with detailed experimental plan, design, cost estimates, milestones, and timelines. Our goal is to be a partner you can count on for your assays development.  We are determined to deliver high-quality custom assay tailored to your needs in a timely manner.

We have a collection of pre-made, high-quality, recombinant proteins and antibodies that may be used for your assay development or immunodetection applications. You can searched to retrieve your protein or antibody of interest by key word, gene or protein synonym, family, classification, disease association, and biological pathway (click here to search). If you cannot find an assay or reagent in our catalog, we can produce it as a custom service project for you.

To discuss your needs and request more information, please contact us by email: This email address is being protected from spambots. You need JavaScript enabled to view it.